About Matt Huentelman, Ph.D. • Neurocientist • Human Genetics Researcher
Dr. Matt Huentelman (pronounced: “Hun’-till-man”) is a Professor in the Neurogenomics Division at the non-profit Translational Genomics Research Institute (or “TGen”) in Phoenix, Arizona. He is the founder and principal scientist behind the MindCrowd research project.
His research interests center on the investigation of the molecular basis of human nervous system health and disease. The ultimate goal of his research is to personalize our medical approach to aging and enable an individualized optimization of brain health in order to facilitate successful cognitive aging. This modern approach to brain aging – termed “Precision Aging” – will enable human cognitive healthspan to better match our lifespan and dramatically reduce the burden of age-related brain diseases on the population.
Dr. Huentelman joined TGen in July of 2004 after completing his doctoral work at the University of Florida's Department of Physiology and Functional Genomics at the McKnight Brain Institute. His undergraduate degree is from Ohio University's Department of Chemistry and Biochemistry at Clippinger Laboratories.
Dr. Huentelman's career includes visiting researcher fellowships in Moscow, Russia at the MV Lomonosov Moscow State University “Biology Faculty” and in the United Kingdom at the University of Bristol’s Department of Physiology. His research is/was supported in part by the National Institutes of Health, the Department of Defense, the Arizona Community Foundation, the Institute for Mental Health Research, Science Foundation Arizona, the Flinn Foundation, and the American Heart Association.
He has published over 225 peer-reviewed manuscripts since 1998 which have been cited over 20,000 times by his peers.
* Postdoctoral Fellow: Neuroscience and Genomics, University of Florida and TGen, 2004-2006
* PhD: Physiology and Functional Genomics, University of Florida, 2003
* BS: Biochemistry, Ohio University, 1998
Representative Recent Publications
* Talboom JS, De Both MD, Naymik MA, Schmidt AM, Lewis CR, Jepsen WM, Håberg AK, Rundek T, Levin BE, Hoscheidt S, Bolla Y, Brinton RD, Schork NJ, Hay M, Barnes CA, Glisky E, Ryan L, Huentelman MJ. Two separate, large cohorts reveal potential modifiers of age-associated variation in visual reaction time performance. NPJ Aging Mech Dis. 2021 Jul 1;7(1):14. doi: 10.1038/s41514-021-00067-6. PMID: 34210964; PMCID: PMC8249619.
* Hooyman A, Talboom JS, DeBoth MD, Ryan L, Huentelman M, Schaefer SY. Remote, unsupervised functional motor task evaluation in older adults across the United States using the MindCrowd electronic cohort. medRxiv [Preprint]. 2021 May 19:2021.05.17.21257333. doi: 10.1101/2021.05.17.21257333. PMID: 34031669; PMCID: PMC8142671.
* Lewis CR, Talboom JS, De Both MD, Schmidt AM, Naymik MA, Håberg AK, Rundek T, Levin BE, Hoscheidt S, Bolla Y, Brinton RD, Hay M, Barnes CA, Glisky E, Ryan L, Huentelman MJ. Smoking is associated with impaired verbal learning and memory performance in women more than men. Sci Rep. 2021 May 13;11(1):10248. doi: 10.1038/s41598-021-88923-z. PMID: 33986309; PMCID: PMC8119711.
* Hay M, Barnes C, Huentelman M, Brinton R, Ryan L. Hypertension and Age-Related Cognitive Impairment: Common Risk Factors and a Role for Precision Aging. Curr Hypertens Rep. 2020 Sep 3;22(10):80. doi: 10.1007/s11906-020-01090-w. PMID: 32880739; PMCID: PMC7467861.
* Huentelman MJ, Talboom JS, Lewis CR, Chen Z, Barnes CA. Reinventing Neuroaging Research in the Digital Age. Trends Neurosci. 2020 Jan;43(1):17-23. doi: 10.1016/j.tins.2019.11.004. Epub 2019 Dec 14. PMID: 31848024.
* Talboom JS, Håberg A, De Both MD, Naymik MA, Schrauwen I, Lewis CR, Bertinelli SF, Hammersland C, Fritz MA, Myers AJ, Hay M, Barnes CA, Glisky E, Ryan L, Huentelman MJ. Family history of Alzheimer's disease alters cognition and is modified by medical and genetic factors. Elife. 2019 Jun 18;8:e46179. doi: 10.7554/eLife.46179. PMID: 31210642; PMCID: PMC6615857.
* Ryan L, Hay M, Huentelman MJ, Duarte A, Rundek T, Levin B, Soldan A, Pettigrew C, Mehl MR, Barnes CA. Precision Aging: Applying Precision Medicine to the Field of Cognitive Aging. Front Aging Neurosci. 2019 Jun 7;11:128. doi: 10.3389/fnagi.2019.00128. PMID: 31231204; PMCID: PMC6568195.
More publications Dr. Huentelman on: PubMed https://pubmed.ncbi.nlm.nih.gov/?term=Huentelman%20MJ%5BAuthor%5D&sort=
PODCASTS FEATURING MATT HUENTELMAN
* Episode 3: The Diagnostic Odyssey - Helios Scholars at TGen 2017 intern... Jan 22, 2018
* Episode 15: MindCrowd—A Study on how the Healthy Brain Works - MindCrowd, launched seven years ago... May 29, 2019
Entries by Matt Huentelman, Ph.D. • Neurocientist • Human Genetics Researcher
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